One of the most important problems in emergency departments is relieving pain in patients with renal colic. The aim of this study was to compare the efficacy of dexmedetomidine and morphine sulfate in the management of acute renal colic pain.Methods: This clinical trial study was performed on 200 patients with acute renal colic pain. Patients were divided into two groups, the first group was injected with dexmedetomidine 1 µg/kg IV, and the second group was injected with morphine at a concentration of 0.1 mg/kg IV and ketorolac. Pain intensity was measured at the time of admission and during the experiment, and the findings were recorded in a questionnaire. The results were analyzed by SPSS

Renal Colic, Dexmedetomidine, Morphine, Renal Patients.