Background: Metachromatic leukodystrophy is a genetic disorder characterized by the accumulation of fatty substances (lipids) in cells, particularly in the brain, spinal cord, and peripheral nerves. A lack of sulfatides,which are enzymes that aid in the breakdown of lipids, causes this buildup. The brain and nervous system gradually lose function as the substance that covers and protects nerve cells (myelin) is damaged

Metachromatic leukodystrophy, Arylsulfatase, Periventricular