Objectives: Oral Cancer is characterized by abnormal growth of cells which have the ability to invade the adjacent tissues and sometimes even distant organs. It has multifactorial etiology and is significantly associated with risk factors of the individual's lifestyle, particularly, chronic use of tobacco, spicy food, alcohol and smoking. Blood groups may directly or indirectly affect the susceptibility of the individual to oral cancer. The present study was done to correlate ABO blood groups with the occurrence of oral cancer and evaluate the risk

Blood groups, Antigen, oral cancer, risk, Innovative technology.