AIM:The purpose of this research was to investigate whether an aqueous extract of CissusQuadrangularis might inhibit the cell proliferation on MCF-7 human breast cancer cells. METHODS:The anti-proliferative properties of CissusQuadrangularis were evaluated using the MTT assay on a human breast cancer cell line. In addition, phase contrast microscopy was used to study the herbal extract-induced morphological changes. All collected data were statistically examined and calculated (SPSS/10 Software Package; SPSS Inc., Chicago,IL, USA) using one-way ANOVA.

C.quadrangularis, Anti-Proliferation, Breast Cancer, Apoptosis